AI-designed DNA controls genes in healthy mammalian cells for first time: Study

A recent study marks the first reported instance of generative AI designing synthetic molecules that can successfully control gene expression in healthy mammalian cells.As a proof-of-concept, the authors of the study asked the AI to design synthetic fragments which activate a gene coding for a fluorescent protein in some cells while leaving gene expression patterns unaltered.

They created the fragments from scratch and dropped them into mouse blood cells, where the sequence fused with the genome at random locations.

The experiments worked exactly as…